منابع مشابه
Physics of bacterial morphogenesis.
Bacterial cells utilize three-dimensional (3D) protein assemblies to perform important cellular functions such as growth, division, chemoreception, and motility. These assemblies are composed of mechanoproteins that can mechanically deform and exert force. Sometimes, small-nucleotide hydrolysis is coupled to mechanical deformations. In this review, we describe the general principle for an under...
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MreB, the bacterial actin homologue, plays a vital role in determining cell shape, but the mechanisms by which it actually functions have remained largely mysterious. Recent studies now shed new light on MreB, demonstrating that it associates with many cell-wall synthesis enzymes, including a newly identified family of proteins that mediate teichoic acid synthesis in Gram-positive bacteria. Fur...
متن کاملBacterial morphogenesis: learning how cells make cells.
Bacteria furnish tractable models for complex biological processes, and morphogenesis is now taking its turn. We can already explain in general terms how such elementary forms as rods and cocci are produced, and the shapes of several individual organisms are coming into focus. In most bacteria shape is maintained by the cell wall, specifically the peptidoglycan layer, which has the attributes o...
متن کاملEmbodied Computation: Applying the Physics of Computation to Artificial Morphogenesis
We discuss the problem of assembling complex physical systems that are structured from the nanoscale up through the macroscale, and argue that embryological morphogenesis provides a good model of how this can be accomplished. Morphogenesis (whether natural or artificial) is an example of embodied computation, which exploits physical processes for computational ends, or performs computations for...
متن کاملBiology meets physics: Reductionism and multi-scale modeling of morphogenesis.
A common reductionist assumption is that macro-scale behaviors can be described "bottom-up" if only sufficient details about lower-scale processes are available. The view that an "ideal" or "fundamental" physics would be sufficient to explain all macro-scale phenomena has been met with criticism from philosophers of biology. Specifically, scholars have pointed to the impossibility of deducing b...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2012
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.00009-12